Biological conduit small gap sleeve bridging method for peripheral nerve injury: regeneration law of nerve fibers in the conduit
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چکیده
منابع مشابه
Use of Chitosan Conduit for Bridging Small-Gap Peripheral Nerve Defect in Sciatic Nerve Transection Model of Rat
Objective-To evaluate effect of chitosan conduit for peripheral nerve regeneration using sciatic nerve transection model in rat Design- Experimental in vivo study. Animals- Sixty healthy male Wistar rats. Procedures-The rats were divided into four experimental groups (n=15) randomly. In sham group the left sciatic nerve was exposed through a gluteal muscle incision and after careful...
متن کاملUse of Chitosan Conduit for Bridging Small-Gap Peripheral Nerve Defect in Sciatic Nerve Transection Model of Rat
Objective-To evaluate effect of chitosan conduit for peripheral nerve regeneration using sciatic nerve transection model in rat DesignExperimental in vivo study. AnimalsSixty healthy male Wistar rats. Procedures-The rats were divided into four experimental groups (n=15) randomly. In sham group the left sciatic nerve was exposed through a gluteal muscle incision and after careful homeostasis the...
متن کاملCan a Small Intestine Segment Be an Alternative Biological Conduit for Peripheral Nerve Regeneration?
BACKGROUND Autologous nerve grafts are used to bridge peripheral nerve defects. Limited sources and donor site morbidity are the major problems with peripheral nerve grafts. Although various types of autologous grafts such as arteries, veins and muscles have been recommended, an ideal conduit has not yet been described. AIMS To investigate the effectiveness of a small intestinal conduit for p...
متن کاملAbstract 134: FK506 Delivering Conduit For Peripheral Nerve Regeneration
PURPOSE: Following a peripheral nerve injury, nerve gaps require grafts or conduits to connect the two nerve ends. There is a clinical need to improve functional recovery following nerve injury and local release of neurotrophic factors is one way to improve outcomes. FK506, an FDA approved small molecule, has been shown to enhance axon growth in vitro and peripheral nerve regeneration in vivo. ...
متن کاملBridging Small-Gap Peripheral Nerve Defect Using Silicone Rubber Chamber in the Rat Sciatic Nerve Transection Model
Despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. Present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat sciatic nerve gap. Fifty- four male Wistar rats were divided into three experimental groups (n = 1...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2015
ISSN: 1673-5374
DOI: 10.4103/1673-5374.150709